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Table 1 Clinical follow-up as carried out by each contributing centre

From: Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report

Centre Series censored Colonoscopy Gynecological examination References for details
Interval Time period Interval From-to Modalities in addition to clinical examination
Norway 2013 3 years 1989–1996 2 years 1989–2013 TV US
CA12–5 		[35]
2 years (1 year when adenoma) 1996–2013
Finland 2014 3 years 1985–2014 1 year 1995–2014 TV US
Endometrial biopsy, CA12–5 		[5, 36, 37]
Sweden 2014 2 years 1990–2000 1 year 1992–2014 TV US
In most: CA 12–5
In some: endometrial biopsy 		[38, 39]
18 months 2000–2014
Denmark 2014 2 years 1991–2014 2 years 1991–2014 TV US [40]
The Netherlands 2013 2–3 years 1987–1996 1–2 years 1994–2005 TV US [10]
2 years 1996–2013 1–2 years 2005–2013 TV US
endometrial biopsy
Newcastle UK 2014 2 years 1995–2014 No fixed policy    
Manchester UK 2014 2 years 1994–2014 1 year 1990–2014 Hysteroscopy
Ovarian US Ca12–5 		[41]
Spain 2013 1–2 years (1 year when age > 40 years) 1999–2013 1 year 1999–2013 TV US  
Melbourne Australia 2014 Annual 1990–2014 Annual 1990–2005 TV US
Endometrial biopsy CA12–5 		https://wiki.cancer.org.au/australiawiki/index.php?oldid=86684
https://wiki.cancer.org.au/australiawiki/index.php?oldid=175314
  2005- Risk reducing surgery only
  1. TV US transvaginal ultrasound
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Hereditary Cancer in Clinical Practice

ISSN: 1897-4287