Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report

Table 1 Clinical follow-up as carried out by each contributing centre

Centre	Series censored	Colonoscopy		Gynecological examination			References for details
Centre	Series censored	Interval	Time period	Interval	From-to	Modalities in addition to clinical examination	References for details
Norway	2013	3 years	1989–1996	2 years	1989–2013	TV US CA12–5	[35]
Norway	2013	2 years (1 year when adenoma)	1996–2013	2 years	1989–2013	TV US CA12–5	[35]
Finland	2014	3 years	1985–2014	1 year	1995–2014	TV US Endometrial biopsy, CA12–5	[5, 36, 37]
Sweden	2014	2 years	1990–2000	1 year	1992–2014	TV US In most: CA 12–5 In some: endometrial biopsy	[38, 39]
Sweden	2014	18 months	2000–2014	1 year	1992–2014	TV US In most: CA 12–5 In some: endometrial biopsy	[38, 39]
Denmark	2014	2 years	1991–2014	2 years	1991–2014	TV US	[40]
The Netherlands	2013	2–3 years	1987–1996	1–2 years	1994–2005	TV US	[10]
The Netherlands	2013	2 years	1996–2013	1–2 years	2005–2013	TV US endometrial biopsy	[10]
Newcastle UK	2014	2 years	1995–2014	No fixed policy
Manchester UK	2014	2 years	1994–2014	1 year	1990–2014	Hysteroscopy Ovarian US Ca12–5	[41]
Spain	2013	1–2 years (1 year when age > 40 years)	1999–2013	1 year	1999–2013	TV US
Melbourne Australia	2014	Annual	1990–2014	Annual	1990–2005	TV US Endometrial biopsy CA12–5	https://wiki.cancer.org.au/australiawiki/index.php?oldid=86684 https://wiki.cancer.org.au/australiawiki/index.php?oldid=175314
Melbourne Australia	2014	Annual	1990–2014		2005-	Risk reducing surgery only

ISSN: 1897-4287