Table 4 Distributions of frequently occurring familial cancers of patients according to BRCA mutation status
Sites of other primary cancers | BRCA (−) (n = 2178) | BRCA (+) (n = 377) | Odds ratio (95% CI) | p value |
|---|---|---|---|---|
Stomach | 162 (7.4%) | 52 (13.8%) | 1.666 (1.183–2.345) | 0.003 |
Pancreas | 38 (1.7%) | 15 (4.0%) | 1.875 (1.006–3.494 | 0.048 |
Liver | 107 (4.9%) | 16 (4.2%) | 0.656 (0.381–1.132) | 0.130 |
Colorectal | 96 (4.4%) | 29 (7.7%) | 1.661 (1.081–2.554) | 0.021 |
Lung | 109 (5.0%) | 33 (8.8%) | 1.586 (1.057–2.380) | 0.026 |
Uterus | 51 (2.3%) | 19 (5.0%) | 2.101 (1.216–3.631) | 0.008 |