Table 8 Number and proportion (%) of Swedish Lynch syndrome family members with onset of primary cancer < 50 years age in relation to gender and MMR gene mutation
From: A retrospective study of extracolonic, non-endometrial cancer in Swedish Lynch syndrome families
CRC No. (%) | EC No (%) | OVC No. (%) | UTC No. (%) | GC No. (%) | SB No. (%) | NMS No. (%) | |
|---|---|---|---|---|---|---|---|
Male | 203 (54) | NA | NA | 8 (27) | 7 (22) | 3 (38) | 5 (42) |
Female | 139 (51) | 92 (45) | 28 (64) | 9 (26) | 7 (27) | 2 (25) | 1 (6) |
MLH1 | 192 (62) | 33 (50) | 5 (63) | 3 (19) | 5 (25) | 2 (25) | 1 (13) |
MSH2 | 119 (54) | 50 (59) | 16 (80) | 14 (34) | 6 (20) | 3(39) | 5 (27) |
MSH6 | 23 (26) | 9 (19) | 6 (42) | – | 4 (67) | – | – |
PMS2 | 8 (30) | – | – | – | – | – | – |