From: A retrospective study of extracolonic, non-endometrial cancer in Swedish Lynch syndrome families
CRC | % | Mean age | ENDO | % | Mean age | OV | % | Mean age | GC | % | Mean age | SmB | % | Mean age | UTC | % | Mean age | Skin | % | Mean age | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MLH1, M | 181 | 78% | 47 (19–80) | NA | NA | NA | NA | NA | NA | 15 | 6% | 61 (19–92) | 3 | 1% | 62 (58–64) | 6 | 3% | 54 (40–66) | 2 | 1% | 64 (55–72) |
MLH1, F | 130 | 65% | 49 (22–82) | 67 | 33% | 52 (36–80) | 8 | 4% | 50 (28–69) | 11 | 5% | 61 (38–84) | 4 | 2% | 56 (37–65) | 10 | 5% | 69 (51–80) | 10 | 8% | 64 (48–78) |
MSH2, M | 135 | 70% | 50 (17–84) | NA | NA | NA | NA | NA | 17 | 9% | 63 (37–80) | 5 | 3% | 55 (48–74) | 21 | 11% | 58 (36–82) | 10 | 7% | 53 (40–65) | |
MSH2, F | 86 | 44% | 49 (23–83) | 86 | 44% | 50 (30–76) | 20 | 10% | 47 (35–80) | 13 | 7% | 56 (38–70) | 3 | 2% | 55 (53–57) | 26 | 13% | 57 (42–83) | 14 | 16% | 68 (54–81) |
MSH6, M | 40 | 58% | 59 (33–82 | NA | NA | NA | NA | NA | 4 | 6% | 42 (32–51) | NA | NA | NA | 6 | 9% | 66 (55–84) | 1 | 3% | 74 (NA) | |
MSH6, F | 48 | 39% | 58 (29–82) | 47 | 39% | 57 (41–80) | 14 | 11% | 53(40–75) | 4 | 3% | 59 (32–77) | NA | NA | NA | 4 | 3% | 65 (51–75) | NA | NA | NA |
PMS2, M | 18 | 72% | 59 (37–83) | NA | NA | NA | NA | NA | 2 | 8% | 67 (56–77) | NA | NA | NA | 1 | 4% | 69 (NA) | NA | NA | NA | |
PMS2, F | 9 | 56% | 60 (23–93) | 3 | 19% | 59 (58–61) | 1 | 6% | 22 (NA) | 1 | 6% | 80 (NA) | NA | NA | NA | 1 | 6% | 62 (NA) | NA | NA | NA |
All male | 374 | 72% | 50 (17–84) | NA | NA | NA | NA | NA | 38 | 7% | 62 (19–92) | 8 | 2% | 57 (48–74) | 34 | 7% | 58 (36–84) | 13 | 3% | 56 (40–72) | |
All female | 273 | 51% | 51 (22–93) | 203 | 38% | 53 (30–80) | 43 | 8% | 49 (22–80) | 29 | 5% | 59 (32–84) | 7 | 1% | 56 (37–65) | 41 | 8% | 61 (42–83) | 24 | 9% | 66 (40–81) |
Total | 1294 | 123% | 51 (17–93) | NA | NA | NA | NA | NA | NA | 67 | 6% | 60 (19–92) | 15 | 1% | 56 (37–74) | 75 | 7% | 60 (36–84) | 37 | 3% | 62 (40–81) |