Table 2 The baseline characteristics of patient group
Nr. | Probands age at diagnosis (years) | Primary cancer site | Morphological subtype | Breast cancersubtype | Tumor grade | Family history |
|---|---|---|---|---|---|---|
1 | 54 | Breast | Ductal | Luminal | missing | Mother and maternal aunt – breast cancer age 60; daughter - polycytemia vera age15, brother – melanoma age 60 |
2 | 40 | Breast | Ductal | Triple-negative* | G3 | Mother - Breast and ovarian cancer age 40 |
3 | 33 and 38 | Left Breast/ Right Breast | Ductal/ Ductal | Triple-negative/ Luminal | G3/G3 | Paternal grandmother - unknown primary gynecological cancer age 50 |
4 | 63 | Breast and Ovaries | Ductal | Triple-negative | G2 | Mother with breast cancer age 55; sister - ovarian cancer age 59 |
5 | 37 | Ovaries | NA | NA | NA | Mother - breast cancer age 64 |
6 | 58 | Breast | Lobular | Luminal | G2 | Mother and maternal aunt – breast cancer age > 60 |
7 | 43 | Breast | Ductal | Triple-negative | G3 | No |
8 | 42 | Breast | Ductal/Medullary | Triple-negative | G2 | Mother - breast cancer age 60 |
9 | 50 | Breast | Ductal | Triple-negative | G3 | Mother - breast cancer age 52 |
10 | 35 | Breast | Ductal | Triple-negative | G3 | Mother - breast cancer age 46 |
11 | 52 | Breast | Ductal | Luminal B HER2 positive | G2 | Mother and maternal aunt – breast cancer age > 50 |
12 | 41 | Breast | Ductal | HER2 positive | G3 | No |
13 | 53 | Breast | Ductal | Triple-negative | missing | No |
14 | 36 | Breast | Ductal | Luminal | missing | No |
15 | 53 | Breast | Ductal | Luminal | missing | Mother and maternal grandmother – breast cancer age > 60 years |
16 | 40 | Breast | Ductal | Luminal B HER2 positive | missing | No |