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Table 2 Prevalence of Gadolinium accumulation in dentate nucleus and globus pallidus; in VHL and TSC groups

From: Central nervous system gadolinium accumulation in patients undergoing periodical contrast MRI screening for hereditary tumor syndromes

Number of MRIs Dentate nucleus Globus pallidus
  accumulation no accumulation % total* accumulation no accumulation % total*
VHL group
 0 to 5 1/9 8/9 11.11% 0/8 8/8 0.00%
 6 to 10 3/7 4/7 42.86% 3/7 4/7 42.86%
 11 to 15 4/7 3/7 57.14% 7/8 1/8 87.50%
 16 to 20 2/3 1/3 66.67% 3/3 0/3 100.00%
  > 20 1/1 0/1 100.00% 2/2 0/2 100.00%
  total: 27    total: 28   
TSC group
 0 to 5 1/4 3/4 25.00% 0/4 4/4 0.00%
 6 to 10 1/2 1/2 50.00% 0/2 2/2 0.00%
 11 to 15 1/5 4/5 20.00% 1/6 5/6 16.67%
 16 to 20 0/2 2/2 0.00% 2/3 1/3 66.67%
  > 20 6/8 2/8 75.00% 7/9 2/9 77.78%
  total: 21    total: 24   
  1. In both groups, the prevalence of patients with hypersignal in the dentate nucleus and globus pallidus increased linearly with the number of Gd enhanced MRIs. The increase was highest in the VHL group
  2. *% total = % of patients with accumulation
  3. Note: data are number of patients, unless indicated otherwise