Parameter | VHL group | TSC group |
---|---|---|
Patients included | 28 | 24 |
Clinical signs of Gadolinium toxicity | 0 | 0 |
Radiological signs of Gadolinium accumulation | 15 | 10 |
Mean age (y) | 39 (16 to 63) | 27 (4 to 67) |
Mean number of MRIs (y) | 10 (0 to >20) | 16 (2 to >20) |
Patient sex | ||
Men | 11 | 11 |
Women | 17 | 13 |
Kidney disease | ||
No kidney disease | 9 | 3 |
Few bilateral cysts | 10 | 5 |
Multiple cysts | 2 | 3 |
Renal cell carcinoma | 7 | 1 |
Angiomyolipomas | / | 12 |
(Ab)normal kidney function | ||
Stage 1 (eGFR normal >90 ml/min/1.73m2) | 25 | 20 |
Gadolinium accumulation | 12/25 | 13/20 |
Stage 2 (eGFR 90–60 ml/min/1.73m2) | 3 | 1 |
Gadolinium accumulation | 2/3 | 1/1 |
Stage 3 (eGFR 30–59 ml/min/1.73m2) | 1 | 3 |
Gadolinium accumulation | 1/1 | 2/3 |
Abnormal liver function | 0 | 0 |