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Table 5 Comparison of patients with and without a pathogenic variant

From: Clinical and genetic characterization of hereditary breast cancer in a Chinese population

Characteristic

without Variants (n,%)

with Variant (n,%)

P value

Patient number

97

23

 

Histology type

  

0.218

 IDC

72 (74.2)

16 (69.6)

 

 DCIS

12 (12.4)

1 (4.3)

 

 Other

13 (13.4)

6 (26.1)

 

Molecular type

  

0.001

 TNBC

12 (12.4)

10 (43.5)

 

 Non-TNBC

72 (74.2)

9 (39.1)

 

 Unknown

13 (13.4)

4 (17.4)

 

Tumor size

  

0.288

  < =2 cm

35 (36.1)

6 (26.1)

 

  > 2 cm

46 (47.4)

10 (43.5)

 

 Unknown

16 (16.5)

7 (30.4)

 

Clinical stage

  

0.537

 0

12 (12.4)

1 (4.3)

 

 I

10 (10.3)

2 (8.7)

 

 II

32 (33.0)

10 (43.5)

 

 III

24 (24.7)

3 (13.0)

 

 IV

4 (4.1)

2 (8.7)

 

 Unknown

15 (15.5)

5 (21.7)

 

Lymph nodes status

  

0.086

 Negative

30 (30.9)

10 (43.5)

 

 Positive

41 (42.3)

4 (17.4)

 

 Unknown

26 (26.8)

9 (39.1)

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