Skip to main content

Table 2 Distribution of multiple-gene variants in two groups of 240 participants

From: Clinical and genetic characterization of hereditary breast cancer in a Chinese population

Variable

No (BC) (%)(n = 120)

No (high-risk group) (%)(n = 120)

P-Value

BRCA1

3(2.5)

0(0.0)

0.247

BRCA2

9(7.5)

2(1.7)

0.031

ATM

1(0.8)

3(2.5)

0.622

MUTYH

2(1.7)

7(5.8)

0.171

BARD1

1(0.8)

1(0.8)

1.0

BRIP1

0(0.0)

1(0.8)

1.0

CHEK2

2(1.7)

0(0.0)

0.498

NBN

1(0.8)

0(0.0)

1.0

PALB2

2(1.7)

0(0.0)

0.498

RAD51C

1(0.8)

0(0.0)

1.0

TP53

1(0.8)

0(0.0)

1.0

No causative variants

97(80.9)

106(88.4)

0.157