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Table 4 Cumulative incidences from 25 years of age and 95% confidence intervals for colorectal cancer and extra-colonic cancer

From: Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report

  

3-year interval (Finnish)

1-2-year interval (non-Finnish)

Current age

Age stop

Obs years

#Ca

Cumulative incidence (%)

95% CI

Obs years

#Ca

Cumulative incidence (%)

95% CI

Colorectal cancer

 All

  25

40

1982

19

12.9

[7.4–18.3]

1299

17

16.4

[9.2–23.7]

  25

50

3301

40

25.4

[18.6–32.3]

2424

36

30.0

[21.7–38.3]

  25

60

4070

47

31.7

[24.0–39.4]

2935

48

44.9

[34.6–55.2]

  25

70

4330

51

39.2

[29.4–48.9]

3094

50

53.8

[39.6–68.0]

 Male

  25

40

1026

12

15.7

[7.5–23.9]

610

9

18.5

[7.2–29.7]

  25

50

1682

25

30.8

[20.7–40.9]

1110

21

37.0

[24.3–49.8]

  25

60

2075

29

36.9

[26.1–47.7]

1288

28

57.8

[41.5–74.0]

  25

70

2189

30

41.1

[28.2–54.0]

1365

28

57.8

[41.5–74.0]

 Female

  25

40

956

7

9.6

[2.8–16.4]

689

8

14.8

[5.3–24.4]

  25

50

1623

15

19.4

[10.6–28.3]

1314

15

24.1

[13.4–34.8]

  25

60

2010

18

26.2

[15.2–37.2]

1646

20

35.2

[22.0–48.3]

  25

70

2156

21

36.4

[22.1–50.6]

1729

22

55.3

[30.5–80.0]

Extra-colonic cancer

 All

  25

40

1982

4

2.7

[0.1–5.3]

1299

3

2.9

[0.0–6.1]

  25

50

3301

24

16.9

[10.7–23.2]

2424

22

17.8

[11.0–24.6]

  25

60

4070

39

32.2

[23.5–40.9]

2934

35

35.3

[24.8–45.7]

  25

70

4330

42

39.7

[28.2–51.2]

3094

41

57.2

[41.0–73.5]

  1. Obs years observation years at age group
  2. #Ca number of cancers during observation
  3. CI confidence interval