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Table 2 Scale for quality assessment

From: ARLTS1 polymorphism is associated with an increased risk of familial cancer: evidence from a meta-analysis

Parameter

Detail

Score

1.Source of cases

Selected from a population or cancer registry

2

Selected from an oncology department or cancer institute

1

No description

0

2.Representativeness of controls

Population

2

Population-hospital mixed

1.5

Hospital

1

No description

0

3.Definition of controls

No history of disease

2

No description of source

0

4.HWEa

Conformity

2

Inconformity

0

5. Total sample size

>1000

2

200–1000

1

<200

0

  1. a If the study did not conform to the HWE (P > 0.05), the study was immediately defined as low quality