Table 2 Other cancers in subjects belonging to Hereditary (n = 1156) and not Hereditary (n = 1062) branches of families with familial ovarian/breast cancer syndrome
From: Hereditary and non-hereditary branches of family eligible for BRCA test: cancers in other sites
Cancer site | Number of cancers in branches | P valuea | |
|---|---|---|---|
Hereditary | Not Hereditary | ||
Breast | 182 | 13 | 0.0001 |
Ovary | 33 | 2 | 0.0001 |
Lung | 38 | 9 | 0.0003 |
Kidney | 23 | 5 | 0.0005 |
Colon | 19 | 16 | n.s.b |
Prostate | 18 | 10 | n.s. |
Larynx | 14 | 4 | 0.03 |
Liver | 13 | 3 | 0.02 |
Gastric | 12 | 9 | n.s. |
Leukemia | 11 | 12 | n.s. |
Pancreas | 6 | 1 | n.s. |
Bladder | 4 | 4 | n.s. |
Melanoma | 3 | 2 | n.s. |
Total | 376/1156 | 90/1062 | 0.0001 |