Anxiety and depression symptoms among women attending group-based patient education courses for hereditary breast and ovarian cancer

Table 5 Mixed linear regression analyses of Hospital Anxiety and Depression Scale, Depression in the study sample

Variables	Not adjusted			Fully adjusted (n = 97 ^a)			Final model ^b (n = 100 ^a)
Variables	b	95% CI	p-value ^c	b	95% CI	p-value ^c	b	95% CI	p-value ^c
Intercept (Depression)				9.98	( 3.73, 16.22)	0.002	7.26	(5.03, 9.49)	< 0.001
Educational status (n = 100)			0.046			0.033			0.013
University	−2.45	(−4.44, −0.47)		−2.31	(−4.42, −0.19)		−2.54	(−4.43, −0.65)
High school	−2.36	(−4.40, −0.32)		−2.66	(−4.76, -0.56)		−2.92	(−4.89, −0.96)
Primary school	0	(reference)		0	(reference)		0	(reference)
Living with someone (n = 100)	−0.24	(−2.10, 1.62)	0.797	0.16	(−1.86, 2.17)	0.877
Children (n = 100)	0.84	(−1.01, 2.68)	0.371	0.87	(−1.19,2.92)	0.404
BOC (n = 100)	1.69	(0.32, 3.05)	0.016	0.73	(−0.90, 2.37)	0.374
FDR/SDR dead due to BOC (n = 100)	−2.25	(−3.83, −0.67)	0.006	−1.85	(−3.58, −0.13)	0.036	−2.59	(−4.17, −1.01)	0.002
Age per 10 years (n = 100)	0.43	(−0.07, 0.93)	0.094	0.16	(−0.47, 0.79)	0.618
Disclosure gene test results/years (n = 98)	−0.11	(−0.25, 0.04)	0.140	−0.11	(−0.25, 0.04)	0.141
Monitoring coping style per 10 (n = 99)	−0.33	(−1.17, 0.51)	0.436	−0.11	(−0.93, 0.72)	0.798
Situation specific self-efficacy (n = 100)	−0.48	(−0.93, −0.04)	0.035	−0.47	(−0.97, 0.03)	0.064
Time	−0.32	(−0.88, 0.24)	0.264	−0.31	(−0.89, 0.28)	0.296

Abbreviations: b estimated regression coefficient, CI confidence interval, FDR first degree relative, SDR second degree relative, BOC Breast or ovarian cancer
^a Number of subjects having completed the whole dataset on at least one occasion during the data collection time
^b Final model: After backward stepwise selection from fully adjusted model at significance level 0.05
^c F-test

ISSN: 1897-4287