Anxiety and depression symptoms among women attending group-based patient education courses for hereditary breast and ovarian cancer

Table 4 Mixed linear regression analyses of Hospital Anxiety and Depression Scale, Anxiety in the study sample

Variables	Not adjusted			Fully adjusted (n = 97 ^a)			Final model ^b (n = 98^a)
Variables	b	95% CI	p-value ^c	b	95% CI	p-value^c	b	95% CI	p-value ^c
Intercept (Anxiety)				16.89	(9.45, 24.32)	< 0.001	17.91	(13.04, 22.78)	< 0.001
Educational status (n = 100)			0.597			0.331
University	−1.21	(−3.76, 1.34)		−1.23	(−3.73, 1.27)
High school	−1.29	(−3.91, 1.32)		−1.50	(−3.99, 0.99)
Primary school	0.00	(reference)		0.00	(reference)
Living with someone (n = 100)	−0.19	(−2.52, 2.14)	0.872	0.49	(−1.93, 2.90)	0.691
Children (n = 100)	0.30	(−2.02, 2.61)	0.801	1.31	(−1.13, 3.76)	0.289
BOC (n = 100)	1.22	(−0.52, 2.96)	0.167	0.12	(−1.83, 2.06)	0.906
FDR/SDR died due to BOC (n = 100)	−2.62	(−4.61, −0.62)	0.011	−2.06	(−4.12, −0.00)	0.050	−2.25	(−4.08, −0.43)	0.016
Age per 10 years (n = 100)	0.03	(−0.61, 0.67)	0.926	0.07	(−0.68, 0.82)	0.862
Disclosure gene test results/years (n = 98)	−0.23	(−0.40, −0.05)	0.012	−0.26	(−0.43, −0.09)	0.003	−0.25	(−0.41, −0.09)	0.002
Monitoring coping style per 10 (n = 99)	0.07	(−0.98, 1.12)	0.899	0.35	(−0.63, 1.32)	0.485
Situation specific self-efficacy (n = 100)	−1.02	(−1.55, −0.49)	< 0.001	−1.10	(−1.70, −0.51)	< 0.001	−0.96	(−1.48, −0.45)	< 0.001
Time	−0.91	(−1.47, −0.35)	0.002	−0.90	(−1.46, −0.33)	0.002	−0.92	(−1.48, −0.35)	0.002

Abbreviations: b estimated regression coefficient, CI confidence interval, FDR first degree relative, SDR second degree relative, BOC Breast or ovarian cancer
^a Number of subjects having completed the included variables on at least one occasion during the data collection time
^b Final model: After backward stepwise selection from fully adjusted model at significance level 0.05
^c F-test

ISSN: 1897-4287