Skip to main content

Table 3 Invasive cancers by tumour characteristics with all cause survival

From: Intensive breast screening in BRCA2 mutation carriers is associated with reduced breast cancer specific and all cause mortality

Selection

Number of cases

Number of deaths

5 years survival (SE)

10 years survival (SE)

p value for 2nd category (e.g. <50 vs 50+)

p value for screened vs no screening for each category

No screening

260

38

0.871 (0.025)

0.728 (0.043)

0.089

 

Screened

68

5

0.917 (0.040)

0.863 (0.065)

  

All (n = 328)

      

 <50 year

208

25

0.895 (0.025)

0.795 (0.040)

0.117

 

 50+ yrs

120

18

0.853 (0.040)

0.647 (0.088)

  

Screened

      

 <50 year

40

3

0.941 (0.041)

0.869 (0.079)

0.690

0.216

 50+ yrs

28

2

0.867 (0.088)

0.867 (0.088)

 

0.214

No screening

      

 <50 year

168

22

0.883 (0.030)

0.777 (0.045)

0.121

 

 50+ yrs

92

16

0.847 (0.045)

0.570 (0.111)

  

All (n = 211)

      

 ER neg

48

3

0.913 (0.048)

0.913 (0.048)

0.130

 

 ER pos

163

23

0.909 (0.028)

0.686 (0.064)

  

Screened

      

 ER neg

14

0

1

1

0.146

0.238

 ER pos

42

5

0.862 (0.065)

0.755 (0.116)

 

0.694

Not screened

      

 ER neg

34

3

0.875 (0.068)

0.875 (0.068)

0.375

 

 ER pos

121

18

0.925 (0.030)

0.665 (0.074)

  

All (n = 237)

      

 Grade 1/2

100

12

0.892 (0.039)

0.740 (0.076)

0.943

 

 Grade 3

137

18

0.887 (0.032)

0.776 (0.050)

  

Screened

      

 Grade 1/2

31

2

0.900 (0.067)

0.900 (0.067)

0.980

0.248

 Grade 3

31

2

0.920 (0.055)

0.920 (0.055)

 

0.185

No screening

      

 Grade 1/2

69

10

0.889 (0.047)

0.668 (0.101)

0.958

 

 Grade 3

106

16

0.876 (0.039)

0.729 (0.062)

  

All (n = 148)

      

 Node neg (0)

75

5

0.958 (0.029)

0.829 (0.076)

0.019

 

 Node pos (1+)

73

14

0.823 (0.054)

0.676 (0.077)

  

Screened

      

 Node neg (0)

41

1

0.962 (0.038)

0.962 (0.038)

0.049

0.209

 Node pos (1+)

20

4

0.821 (0.094)

0.718 (0.127)

 

0.706

No screening

      

 Node neg (0)

34

4

0.955 (0.044)

0.728 (0.123)

0.164

 

 Node pos (1+)

53

10

0.822 (0.067)

0.667 (0.089)

  

All (n = 186)

      

 <20 mm

108

14

0.922 (0.029)

0.752 (0.058)

0.884

 

 20 + mm

78

10

0.865 (0.048)

0.778 (0.064)

  

Screened

      

 <20 mm

44

4

0.909 (0.051)

0.818 (0.098)

0.624

0.441

 20 + mm

15

1

0.917 (0.080)

0.917 (0.080)

 

0.277

No screening

      

 <20 mm

64

10

0.939 (0.034)

0.717 (0.086)

0.792

 

 20 + mm

63

9

0.849 (0.057)

0.731 (0.081)

  
  1. Bold type indicates statistically significant results