Skip to main content

Advertisement

Springer Nature is making Coronavirus research free. View research | View latest news | Sign up for updates

Table 3 Invasive cancers by tumour characteristics with all cause survival

From: Intensive breast screening in BRCA2 mutation carriers is associated with reduced breast cancer specific and all cause mortality

Selection Number of cases Number of deaths 5 years survival (SE) 10 years survival (SE) p value for 2nd category (e.g. <50 vs 50+) p value for screened vs no screening for each category
No screening 260 38 0.871 (0.025) 0.728 (0.043) 0.089  
Screened 68 5 0.917 (0.040) 0.863 (0.065)   
All (n = 328)       
 <50 year 208 25 0.895 (0.025) 0.795 (0.040) 0.117  
 50+ yrs 120 18 0.853 (0.040) 0.647 (0.088)   
Screened       
 <50 year 40 3 0.941 (0.041) 0.869 (0.079) 0.690 0.216
 50+ yrs 28 2 0.867 (0.088) 0.867 (0.088)   0.214
No screening       
 <50 year 168 22 0.883 (0.030) 0.777 (0.045) 0.121  
 50+ yrs 92 16 0.847 (0.045) 0.570 (0.111)   
All (n = 211)       
 ER neg 48 3 0.913 (0.048) 0.913 (0.048) 0.130  
 ER pos 163 23 0.909 (0.028) 0.686 (0.064)   
Screened       
 ER neg 14 0 1 1 0.146 0.238
 ER pos 42 5 0.862 (0.065) 0.755 (0.116)   0.694
Not screened       
 ER neg 34 3 0.875 (0.068) 0.875 (0.068) 0.375  
 ER pos 121 18 0.925 (0.030) 0.665 (0.074)   
All (n = 237)       
 Grade 1/2 100 12 0.892 (0.039) 0.740 (0.076) 0.943  
 Grade 3 137 18 0.887 (0.032) 0.776 (0.050)   
Screened       
 Grade 1/2 31 2 0.900 (0.067) 0.900 (0.067) 0.980 0.248
 Grade 3 31 2 0.920 (0.055) 0.920 (0.055)   0.185
No screening       
 Grade 1/2 69 10 0.889 (0.047) 0.668 (0.101) 0.958  
 Grade 3 106 16 0.876 (0.039) 0.729 (0.062)   
All (n = 148)       
 Node neg (0) 75 5 0.958 (0.029) 0.829 (0.076) 0.019  
 Node pos (1+) 73 14 0.823 (0.054) 0.676 (0.077)   
Screened       
 Node neg (0) 41 1 0.962 (0.038) 0.962 (0.038) 0.049 0.209
 Node pos (1+) 20 4 0.821 (0.094) 0.718 (0.127)   0.706
No screening       
 Node neg (0) 34 4 0.955 (0.044) 0.728 (0.123) 0.164  
 Node pos (1+) 53 10 0.822 (0.067) 0.667 (0.089)   
All (n = 186)       
 <20 mm 108 14 0.922 (0.029) 0.752 (0.058) 0.884  
 20 + mm 78 10 0.865 (0.048) 0.778 (0.064)   
Screened       
 <20 mm 44 4 0.909 (0.051) 0.818 (0.098) 0.624 0.441
 20 + mm 15 1 0.917 (0.080) 0.917 (0.080)   0.277
No screening       
 <20 mm 64 10 0.939 (0.034) 0.717 (0.086) 0.792  
 20 + mm 63 9 0.849 (0.057) 0.731 (0.081)   
  1. Bold type indicates statistically significant results