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Table 2 Tumour and age characteristics in intensively screened and unscreened women

From: Intensive breast screening in BRCA2 mutation carriers is associated with reduced breast cancer specific and all cause mortality

   

MRI/mammography

Mammography

No screening

Total

p value

In situ (n = 33, 79.1 %)

 

Ductal

10 (100)

9 (100)

14 (100)

33 (100)

1.0

 

Lobular

0 (0)

0 (0)

0 (0)

0 (0)

 

Invasive breast cancer (n = 328, 90.9 %)

Type (n = 328)

Ductal

24 (96.0)

41 (95.3)

244 (93.8)

309 (94.2)

 
 

Lobular

1 (4.0)

1 (2.3)

16 (6.2)

18 (5.5)

 
 

Mixed

0 (0)

1 (2.3)

0 (0)

1 (0.3)

 

Age groups (n = 328)

<50 years

17 (68.0)

23 (53.5)

168 (64.6)

208 (63.4)

0.330

 

> = 50 Years

8 (32.0)

20 (46.5)

92 (35.4)

120 (36.6)

 

Nodes (n = 148)

0

18 (78.3)

23 (60.5)

34 (39.1)

75 (50.7)

 
 

1

2 (8.7)

8 (21.1)

17 (19.5)

27 (18.2)

 
 

2–3

1 (4.3)

6 (15.8)

17 (19.5)

24 (16.2)

 
 

4–5

0 (0)

1 (2.6)

9 (10.3)

10 (6.8)

 
 

6+

2 (8.7)

0 (0.0)

10 (11.5)

12 (8.1)

 
 

Missing

2

5

173

180

 

Nodes (n = 148)

Negative

18 (78.3)

23 (60.5)

34 (39.1)

75 (50.7)

0.001

 

Positive

5 (21.7)

15 (39.5)

53 (60.9)

73 (49.3)

 

ER-status (n = 211)

Negative

3 (18.8)

11 (27.5)

34 (21.9)

48 (22.7)

0.698

 

Positive

13 (81.3)

29 (72.5)

121 (78.1)

163 (77.3)

 
 

Missing

9

3

105

117

 

Grade (n = 237)

1

1 (4.3)

4 (10.3)

6 (3.4)

11 (4.6)

 
 

2

11 (47.8)

15 (38.5)

63 (36.0)

89 (37.6)

 
 

3

11 (47.8)

20 (51.3)

106 (60.6)

137 (57.8)

 
 

Missing

2

4

86

91

 

Grade (n = 237)

1/2

12 (52.2)

19 (48.7)

69 (39.4)

100 (42.2)

0.338

 

3

11 (47.8)

20 (51.3)

106 (60.6)

137 (57.8)

 

Censored (n = 328)

Alive

25 (100)

38 (88.4)

222 (85.4)

285 (86.9)

0.112

 

Dead

0 (0.0)

5 (11.6)

38 (14.6)

43 (13.1)

 

Size (n = 186)

<10

9 (42.9)

10 (26.3)

9 (7.1)

28 (15.1)

 
 

10 – 19.9

8 (38.1)

17 (44.7)

55 (43.3)

80 (43.0)

 
 

20 – 29.9

3 (14.3)

9 (23.7)

36 (28.3)

48 (25.8)

 
 

30 – 39.9

0 (0.0)

1 (2.6)

12 (9.4)

13 (7.0)

 
 

40 – 49.9

0 (0.0)

1 (2.6)

7 (5.5)

8 (4.3)

 
 

> = 50

1 (4.8)

0 (0.0)

8 (6.3)

9 (4.8)

 
  

Missing

4

5

133

142

 
 

Size (n = 186)

<20

17 (81.0)

27 (71.1)

64 (50.4)

108 (58.1)

0.006

  

> = 20

4 (19.0)

11 (28.9)

63 (49.6)

78 (41.9)