Intensive breast screening in BRCA2 mutation carriers is associated with reduced breast cancer specific and all cause mortality

Table 1 Combined MRI/mammography, mammography and unscreened BRCA2 mutation carriers survival from diagnosis

	Number	10-year survival all causes (95 % CI)	Log Rank (Mantel-Cox) P value for overall survival compared to unscreened	10-year survival breast cancer (95 % CI)	Log Rank (Mantel-Cox) P value overall survival compared to unscreened
Unscreened	274	70.8 (62.2 to 79.4)		74.6 (66.6 to 82.6)
MRI/mammography	34	100 %	0.026	100 %	0.035
	6 prevalent
	26 incident
	2 Interval
Mammography	53	85.5 (72.6 to 98.4)	0.142	85.5 (72.6 to 98.4)	0.196
	9 prevalent
	36 incident
	8 Interval
Any screening	87 (5 detected on mammography only in MRI group and 6 with both modalities)	89.5 (79.5 to 99.5)	0.017	89.5 (79.5 to 99.5)	0.029

ISSN: 1897-4287