Status BRCA1 | Wild type (n = 108) | Germline mutation (n = 17) | Statistics | p value |
---|---|---|---|---|
Median (range) age at diagnosis in years | 56 (28–85) | 47 (39–70) | −2.859a | 0.004 |
Performance status WHO: | ||||
▪ 0 | 15 | 4 | ||
▪ Other | 93 | 13 | 0.44b | 0.51 |
FIGO stage: | ||||
▪ Early (I, II) | 22 | 3 | ||
▪ Advanced (III,IV) | 86 | 14 | 0.07b | 0.95 |
Chemotherapy regimen: | ||||
▪ With paclitaxel | 97 | 16 | ||
▪ Without paclitaxel | 11 | 1 | 0.01b | 0.91 |
Chemotherapy regimen: | ||||
▪ With cisplatin | 47 | 8 | ||
▪ With carboplatin | 61 | 9 | 0.1c | 0.75 |
Type of histology: | ||||
▪ Serous | 57 | 11 | ||
▪ Other | 51 | 6 | 0.84c | 0.36 |
Grading: | ||||
▪ 1 and 2 | 38 | 7 | ||
▪ 3 and unspecified | 70 | 10 | 0.23c | 0.63 |
Primary surgery: | ||||
▪ Optimal (<1 cm) | 68 | 9 | ||
▪ Suboptimal (>1 cm) | 40 | 8 | 0.62c | 0.43 |