Skip to main content

Table 3 Results of treatment of patients with BRCA1-OC depending on the population, microscopic and clinical characteristics

From: Prognostic factors in Polish patients with BRCA1-dependent ovarian cancer

Population, microscopic and clinical characteristics No. of patients 5-year overall survival
No. of patients %
The number of patients with BRCA1 gene mutation 66 29 43.9
a Coexisting neoplasms
 - no 57 28 49.1
 - breast cancer 9 1 11.1
a The total extent of cytoreduction
 - optimal 34 20 58.8
 - suboptimal 32 9 28.1
a Staging FIGO (2009)
 - I 4 4 100.0
 - II 8 5 62.5
 - III 50 19 38.0
 - IV 4 1 25.0
a Histological type
 - serous 27 11 40.7
 - endometrial 23 14 60.9
 - undifferentiated 8 1 12.5
 - mucous 4 2 50.0
 - clear cell 2 1 50.0
 - mezonefroid 2 0 0
a CA125 concentration at the beginning of treatment
 - < 285,5 31 21 67.7
 - ≥285,5 35 8 22.9
a CA125 concentration at the end of treatment
 - <12,5 34 22 64.7
 - ≥12,5 22 7 31.8
  1. a Statistically significant differences, log rank test, p <0.05