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Table 2 Comparison of long-term outcome in patients with BRCA-OC

From: Prognostic factors in Polish patients with BRCA1-dependent ovarian cancer

Author, year of publication

No. of patients

Population

Overall 5-year survival

Median survival

Rubin 1996 [23]

53

BRCA1/2-OC

~60 %a

~80 monthsa

Pharoah 1999 [7]

127

BRCA1/2-OC

21 %

20,6 months

Boyd 2000 [10]

67

BRCA1-OC

~50 %a

~60 monthsa

Ramus 2001 [24]

15

BRCA1-OC

~25 %a

52 months

Cass 2003 [11]

33

BRCA1/2-OC

65 %

91 months

Majdak 2005b [3]

18

BRCA1-OC

~33 %a

~28 monthsa

Chetrit 2008 [8]

213

BRCA1/2-OC

46 %

53,7 months

Tan 2008 [25]

22

BRCA1/2-OC

~65 %a

8,4 years

Kringen 2005 [26]

30

BRCA1/2-OC

33,3 %

-

Lacour 2011 [27]

95

BRCA1/2-OC

~25 %a

101,7 months

Hyman 2012 [9]

30

BRCA1-OC

~60 %a

6 years

Vencken 2013 [28]

245

BRCA1-OC

62 %

6 years

Bolton 2012 [29]

909

BRCA1-OC

44 %

4,6 years

Own material

66

BRCA1-OC

43,9 %

32,3 months

  1. a Data extrapolated from the Kaplan-Meier curves
  2. b Polish patients population