Skip to main content

Table 2 Comparison of long-term outcome in patients with BRCA-OC

From: Prognostic factors in Polish patients with BRCA1-dependent ovarian cancer

Author, year of publication No. of patients Population Overall 5-year survival Median survival
Rubin 1996 [23] 53 BRCA1/2-OC ~60 %a ~80 monthsa
Pharoah 1999 [7] 127 BRCA1/2-OC 21 % 20,6 months
Boyd 2000 [10] 67 BRCA1-OC ~50 %a ~60 monthsa
Ramus 2001 [24] 15 BRCA1-OC ~25 %a 52 months
Cass 2003 [11] 33 BRCA1/2-OC 65 % 91 months
Majdak 2005b [3] 18 BRCA1-OC ~33 %a ~28 monthsa
Chetrit 2008 [8] 213 BRCA1/2-OC 46 % 53,7 months
Tan 2008 [25] 22 BRCA1/2-OC ~65 %a 8,4 years
Kringen 2005 [26] 30 BRCA1/2-OC 33,3 % -
Lacour 2011 [27] 95 BRCA1/2-OC ~25 %a 101,7 months
Hyman 2012 [9] 30 BRCA1-OC ~60 %a 6 years
Vencken 2013 [28] 245 BRCA1-OC 62 % 6 years
Bolton 2012 [29] 909 BRCA1-OC 44 % 4,6 years
Own material 66 BRCA1-OC 43,9 % 32,3 months
  1. a Data extrapolated from the Kaplan-Meier curves
  2. b Polish patients population