Table 1 Proportion of different cancer types in non-BRCA families
From: Tumour spectrum in non-BRCA hereditary breast cancer families in Sweden
Cancer site | Observed number | Proportion [%] | LL 95Â % | UL 95Â % | Proportion [%] in Sweden 1970 | Proportion [%] in Sweden 2010 | Reference outside CI |
|---|---|---|---|---|---|---|---|
Prostate | 103 | 14.57 | 12.02 | 17.26 | 6.98 | 11.95 | CI above reference |
Ovary/Fallopian tube | 73 | 10.33 | 8.2 | 12.59 | 4.51 | 1.93 | CI above reference |
Colon | 47 | 6.65 | 4.81 | 8.49 | 7.75 | 7.21 | No |
Lung | 45 | 6.36 | 4.67 | 8.2 | 5.5 | 5.53 | No |
Uterus | 45 | 6.36 | 4.67 | 8.2 | 3.07 | 2.64 | CI above reference |
Malignant melanoma | 35 | 4.95 | 3.39 | 6.65 | 4.28 | 9.04 | No |
Brain and nervous system | 34 | 4.81 | 3.25 | 6.51 | 7.66 | 6.12 | No |
Pancreas | 33 | 4.67 | 3.11 | 6.22 | 2.79 | 1.54 | CI above reference |
Uterine cervix | 33 | 4.67 | 3.11 | 6.22 | 4.85 | 2.98 | No |
Stomach | 28 | 3.96 | 2.55 | 5.52 | 6.51 | 1.49 | No |
Abdomen UNS | 25 | 3.54 | 2.26 | 4.95 | 0 | 0 | CI above reference |
Urinary tract | 24 | 3.39 | 2.12 | 4.81 | 3.59 | 3.72 | No |
Kidney | 23 | 3.25 | 1.98 | 4.67 | 4.13 | 2.28 | No |
Leukemia | 23 | 3.25 | 1.98 | 4.67 | 4.55 | 5.25 | No |
Rectum and anus | 21 | 2.97 | 1.84 | 4.24 | 3.73 | 3.72 | No |
Lymphoma | 21 | 2.97 | 1.84 | 4.24 | 5.75 | 6.28 | CI below reference |
Liver | 15 | 2.12 | 1.13 | 3.25 | 0.28 | 0.13 | CI above reference |
Biliary tract | 13 | 1.84 | 0.99 | 2.83 | 2.85 | 1.47 | No |
Skin | 13 | 1.84 | 0.99 | 2.83 | 2.4 | 7.92 | No |
Oesophagus | 9 | 1.27 | 0.57 | 2.12 | 0.76 | 0.59 | No |
Connective tissue | 8 | 1.13 | 0.42 | 1.98 | 1.43 | 1.15 | No |
Multiple myeloma | 8 | 1.13 | 0.42 | 1.98 | 1.13 | 1.05 | No |
Testis | 6 | 0.85 | 0.28 | 1.56 | 1.52 | 3.27 | No |
Thyroid | 5 | 0.71 | 0.14 | 1.41 | 1.97 | 2.72 | CI below reference |
Mouth | 4 | 0.57 | 0.14 | 1.13 | 0.91 | 1.2 | No |
Endocrine | 4 | 0.57 | 0.14 | 1.13 | 2.31 | 2.01 | CI below reference |
Lip | 2 | 0.28 | 0 | 0.71 | 0.65 | 0.18 | No |
Salivary gland | 2 | 0.28 | 0 | 0.71 | 0.54 | 0.47 | No |
Larynx | 2 | 0.28 | 0 | 0.71 | 0.56 | 0.29 | No |
Unspecified | 2 | 0.28 | 0 | 0.71 | 3.29 | 2.36 | CI below reference |
Small intestine | 1 | 0.14 | 0 | 0.42 | 0.43 | 0.47 | CI below reference |
Tongue | 0 | 0 | 0 | 0 | 0.22 | 0.45 | CI below reference |
Peritoneum | 0 | 0 | 0 | 0 | 0.03 | 0.16 | CI below reference |
Middle ear | 0 | 0 | 0 | 0 | 0.38 | 0.17 | CI below reference |
Mediastinum | 0 | 0 | 0 | 0 | 0.01 | 0.07 | CI below reference |
Placenta | 0 | 0 | 0 | 0 | 0.11 | 0.05 | CI below reference |
Female genital | 0 | 0 | 0 | 0 | 0.53 | 0.42 | CI below reference |
Male genital | 0 | 0 | 0 | 0 | 0.24 | 0.14 | CI below reference |
Eye | 0 | 0 | 0 | 0 | 0.55 | 0.45 | CI below reference |
Skeleton | 0 | 0 | 0 | 0 | 0.82 | 0.57 | CI below reference |
Polycytemia vera | 0 | 0 | 0 | 0 | 0.37 | 0.26 | CI below reference |
Myelofibrosis | 0 | 0 | 0 | 0 | 0.03 | 0.32 | CI below reference |