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Table 4 CHEK2 variant c.470C occurrence in patients with differentiated thyroid carcinoma (DTC) in the age groups due to the age at onset

From: The c.470 T > C CHEK2 missense variant increases the risk of differentiated thyroid carcinoma in the Great Poland population

age group (years)

Number of patients

Number of patients with genotypes TC+CC (frequency)

OR

CI

p-value

0 - 30

80

7 (8.75%)

1.1

[0.41-2.74]

0.763

30 - 40

98

8 (8.16%)

1.0

[0.40-2.40]

0.918

40 – 50

115

8 (6.96%)

0.8

[0.33-1.92]

0.669

50 - 60

133

17 (12.78%)

2.2

[1.07-4.38]

0.016

60 -100

105

2 (1.9%)

0.2

[0.02-0.75]

0.008

  1. In bold: statistically significant numbers with 95% confidence intervals.