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Table 4 Clinical and pathological features of 8 MEN2A patients with pheochromocytoma

From: Molecular diagnosis and comprehensive treatment of multiple endocrine neoplasia type 2 in Southeastern Chinese

Patient

Gender

RETmutation

Age at diagnosis PHEO

Temporal relation of PHEO to MTC

NE/E/DA (ng/L)

Tumor (size, cm)

Operative procedure

Follow-up

F1-II4

F

C634F

26

Preceding

246.0/36.3/61.5

L, 3.3

Left OPE

163

F2-II1

M

C634Y

35

Concomitant

399.0/48.2/43.0

R, 2.5

Right OPE

74

F3-III7

F

C634Y

36

Preceding

827.5/106.0/88.5

R, 4.0

Right OPE

71

F4-II3

M

C634Y

47

Succeeding

657.0/144.2/40.0

L, 2.3

Left LPE

8

F5-II1

M

C634R

34

Succeeding

1305.0/1270.3/243.6

L, 10 ; R, 3.5

heterochronous bilateral OPE

252

F5-II7

M

C634R

47

Succeeding

667.7/92.5/78.3

R, 2.9

Right LPE

12

F6-III2

M

C634R

21

Concomitant

69.9/12.6/10.2

L, 3.5

Left LPE

24

F7-II2

F

C618R

40

Succeeding

681.2/89.4/67.0

L, 2.9

Left LPE

102

  1. Note: OPE, open PHEO excision; LPE, laparoscopic PHEO excision; NE (norepinephrine): normal, 0 ~ 600 ng/L; E (epinephrine): normal, 0 ~ 100 ng/L; DA(dopamine): normal, 0 ~ 100 ng/L.