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Table 3 Characteristics of 13RET-mutation carriers

From: Molecular diagnosis and comprehensive treatment of multiple endocrine neoplasia type 2 in Southeastern Chinese

Patient/Gender RETmutation Age Pre-Ct (ng/L) CEA (ng/ml) Tumor size* (cm): L/R Operative procedure Histology pTNM LNM Post-Ct (ng/L) Interval time (years)
F3-III8/F C634Y 41 1744.0 57.9 1.4/3.2 Reject operation - - - - 18
F3-III9/F C634Y 37 206.0 12.2 1.0/0.7 Reject operation - - - - 18
F3-IV1/M C634Y 22 11.8 1.8 -/0.3 Reject operation - - - - 18
F3-IV4/F C634Y 9 9.8 0.7 0.3/0.2 Reject operation - - - - 18
F4-III2/F C634Y 18 118.0 6.8 1.0/1.0 TT + B-VI MTC T1N0M0 0/5 <2.0 17
F5-III4/F C634R 19 24.3 2.9 0.3/0.2 TT MTC T1N0M0 NO <2.0 17
F6-III2/M C634R 21 20.9 2.7 0.5/0.7 TT + B-VI MTC T1N0M0 0/3 <2.0 26
F6-III4/M C634R 21 1769.0 119.6 1.1/1.0 TT + B-VI + R-LND MTC T1N1bM0 20/59 975.0 23
F6-III5/F C634R 19 71.4 3.3 0.5/1.0 TT + B-VI MTC T1N0M0 0/1 <2.0 26
F7-III2/F C618R 26 487.6 25.9 2.0/2.5 Reject operation - -   - 17
F8-II2/F C618Y 78 1758.0 106.0 3.0/3.5 Reject operation - -   - 19
F8-III5/M C618Y 53 <2.0 2.2 −/− Awaiting surgery - -   - 19
F8-IV5/F C618Y 26 5.8 2.0 −/− TT CCH - NO <2.0 19
  1. Note: Ct (basal serum Ct): normal <8.4 ng/L for male and <5.0 for female by FACLIA ; CEA (carcinoembryonic antigen): normal ≤ 5.0 ng/ml; Pre-Ct, pre-surgical Ct; Post-Ct, post-surgical Ct; TT, total thyroidectomy; B-VI, bilateral level VI lymph node dissection; R/ L -LND, right/ left lymph neck dissection.
  2. *Tumor size was measured by ultrasonography.