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Table 1 Clinical and molecular features of nine MEN2 families

From: Molecular diagnosis and comprehensive treatment of multiple endocrine neoplasia type 2 in Southeastern Chinese

Family Numbers of patients Sex ratio (M/F) Age range (years) RETmutation MTC age at onset (mean years) PHEO numbers/Age at diagnosis (mean years)
MEN2A       
  F1 2 1/1 28-58 p.C634F 43.0 1/26
 F2 1 1/0 35 p.C634Y 35.0 1/35
 F3 6 2/4 9-44 p.C634Y 30.2 1/36
 F4 3 2/1 18-44 p.C634Y 27.3 1/47
 F5 3 2/1 19-32 p.C634R 24.7 2/40.5
 F6 6 4/2 19-65 p.C634R 33.5 1/21
 F7 3 1/2 21-36 p.C618R 27.3 1/40
FMTC       
 F8 8 2/6 24-78 p.C618Y 45.3 -
MEN2B       
 F9 1 1/0 33 p.M918T 33 -