Skip to main content

Table 1 Clinical and molecular features of nine MEN2 families

From: Molecular diagnosis and comprehensive treatment of multiple endocrine neoplasia type 2 in Southeastern Chinese

Family

Numbers of patients

Sex ratio (M/F)

Age range (years)

RETmutation

MTC age at onset (mean years)

PHEO numbers/Age at diagnosis (mean years)

MEN2A

      

  F1

2

1/1

28-58

p.C634F

43.0

1/26

 F2

1

1/0

35

p.C634Y

35.0

1/35

 F3

6

2/4

9-44

p.C634Y

30.2

1/36

 F4

3

2/1

18-44

p.C634Y

27.3

1/47

 F5

3

2/1

19-32

p.C634R

24.7

2/40.5

 F6

6

4/2

19-65

p.C634R

33.5

1/21

 F7

3

1/2

21-36

p.C618R

27.3

1/40

FMTC

      

 F8

8

2/6

24-78

p.C618Y

45.3

-

MEN2B

      

 F9

1

1/0

33

p.M918T

33

-

Back to article page

Hereditary Cancer in Clinical Practice

ISSN: 1897-4287