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Table 6 SNPs associated with ovarian cancer risk

From: Identification of new genes associated with breast and ovarian cancer risk. Advances of BCAC, CIMBA and OCAC

Gene / SNP

Ovarian cancer risk

OCAC manuscript

CDKN2A, rs3731257

CDKN1B, rs2066827

OR 0.91, 95% CI 0.85-0.98, p=0.008

OR 0.93, 95% CI 0.87-0.995, p=0.036

Gayther et al., Cancer Res 2007

TP53, 23 SNPs:

rs2287498

rs12951053

ORper-allele 1.30, 95% CI 1.07-1.57

ORper-allele 1.19, 95% CI 1.01-1.38

Schildkraut et al., Cancer Res 2009

NMI, rs11683487

OR 0.89, 95% CI 0.80-0.99, p=0.032

Quaye et al., BJC 2009

CYP3A4, rs2740574

ORhom 2.81, 95% CI 1.20-6.56, p=0.017

Pearce et al., BJC 2009

9p22.2, rs3814113

OR 0.82, 95% CI 0.79-0.86, p=5.1×10-19

serous tumors: OR 0.77, 95% CI 0.73-0.81, p=4.1×10-21

Song et al., Nat Genet 2009