Table 4 SNPs associated with breast cancer risk in BRCA1/2 carriers

RAD51, rs11683487

BRCA2: HR_hom 3.18, 95% CI 1.39-7.27, p=0.0007

Antoniou et al. AJHG 2007

TNRC9, rs3803662

FGFR2, rs2981582

MAP3K1, rs889312

BRCA1/2: HR 1.13, 95% CI: 1.06-1.20, p_trend= 5 × 10^-5

BRCA2: HR 1.32, 95% CI: 1.20-1.45, p_trend=1.7 × 10^-8

BRCA2: HR 1.12, 95% CI: 1.02-1.24, p_trend=0.02

Antoniou et al. AJHG 2008

2q35, rs13387042

LSP1, rs3817198

2q35, rs13387042

BRCA1: HR 1.14, 95% CI: 1.04-1.25, p=0.0047

BRCA2: HR 1.16, 95% CI: 1.07-1.25, p_trend=2.8 × 10^-4

HR 1.18 95% CI: 1.04-1.33, p=0.0079

Antoniou et al. Hum Mol Genet 2008