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Table 1

From: The importance of tumor studies in the initial evaluation for Lynch syndrome: a comparison of MMR positive and negative patients

  Gene CRC
  MLH1 MSH2 Diagnosed Age at diagnosis (SD) Proximal location Synchronous / metachronous
Mutation Positive n=61 21 (34.4%) 40 (65.6%) 52 (85.2%) 43.4 (11.5) 25 (48.1%) 17 (32.7%)
Mutation Negative n=31 20 (64.5%) 11 (35.5%) 24 (77.4%) 50.0 (11.7) 15 (62.5%) 5 (20.8%)