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Table 1

From: The importance of tumor studies in the initial evaluation for Lynch syndrome: a comparison of MMR positive and negative patients

 

Gene

CRC

 

MLH1

MSH2

Diagnosed

Age at diagnosis (SD)

Proximal location

Synchronous / metachronous

Mutation Positive n=61

21 (34.4%)

40 (65.6%)

52 (85.2%)

43.4 (11.5)

25 (48.1%)

17 (32.7%)

Mutation Negative n=31

20 (64.5%)

11 (35.5%)

24 (77.4%)

50.0 (11.7)

15 (62.5%)

5 (20.8%)