Table 1

Proband

Affected

3

First Degree Relatives(FDR)

Each FDR

3 each

1-FDR<50-yr, including proband)

3

1-FDR–same side family

Extra 3

Second Degree relatives(SDR)

Each SDR

1 each

>1-SDR<50-yr

1

>1-SDR–same side family

Extra 1*

Combination FDR and SDR

1-FDR and any SDR–same side family

2*