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Table 1 Clinical characteristics of individuals referred for personal and/or family history of CRC by race

From: Racial differences in a high-risk colorectal cancer referral population: a single-center experience

  AA Caucasian p-value
Personal and/or family history of CRC    
Total number of individuals 254 949  
Total number families (% of total individuals) 68 (26.8) 617 (65.0) 0.002
Median # CRC affected family members (range) 1 (1-7) 1 (1-14)  
Average number CRC affected family members < 50 years 0.35 0.46  
Number with polyps (%) 6 (2.4) 43 (4.5) 0.12
Genetic testing (%) 16 (6.3) 106 (11.2) 0.02
Personal History of CRC    
Total number (% of total) 32 (12.6) 86 (9.1) 0.09
Age years (mean) 48.6 49.9 0.65
% female 82.1 60.5 0.04
Revised Bethesda + (%) 22 (68.8) 49 (57.0) 0.25
Amsterdam II + (%) 5 (15.6) 17 (19.8) 0.61
PREMM1,2 score 17.06 16.12 0.81
Genetic testing (%) 10 (31.2) 42 (48.8) 0.09
  1. CRC, colorectal cancer; AA, African American; Genetic testing category includes mismatch repair genes and APC; PREMM1,2 score obtained using publicly available calculator