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Table 1 Clinical characteristics of individuals referred for personal and/or family history of CRC by race

From: Racial differences in a high-risk colorectal cancer referral population: a single-center experience

 

AA

Caucasian

p-value

Personal and/or family history of CRC

   

Total number of individuals

254

949

 

Total number families (% of total individuals)

68 (26.8)

617 (65.0)

0.002

Median # CRC affected family members (range)

1 (1-7)

1 (1-14)

 

Average number CRC affected family members < 50 years

0.35

0.46

 

Number with polyps (%)

6 (2.4)

43 (4.5)

0.12

Genetic testing (%)

16 (6.3)

106 (11.2)

0.02

Personal History of CRC

   

Total number (% of total)

32 (12.6)

86 (9.1)

0.09

Age years (mean)

48.6

49.9

0.65

% female

82.1

60.5

0.04

Revised Bethesda + (%)

22 (68.8)

49 (57.0)

0.25

Amsterdam II + (%)

5 (15.6)

17 (19.8)

0.61

PREMM1,2 score

17.06

16.12

0.81

Genetic testing (%)

10 (31.2)

42 (48.8)

0.09

  1. CRC, colorectal cancer; AA, African American; Genetic testing category includes mismatch repair genes and APC; PREMM1,2 score obtained using publicly available calculator