Table 1
From: Familial Adenomatous Polyposis (FAP) in 9 Hispanic women
Country of Origin* | Diagnosis | Polyps | Extra-colonic Findings | Family History** | Gene Analysis | ||
|---|---|---|---|---|---|---|---|
Cancer | Age | exon | |||||
MX | Cholangio | 48 | >100 | gastric polyp | mom-co-44, sis-co-32+pan-64, sis-co-38, cousin-co-38 | Q1062X | 15 |
MX | Rectal | 35 | >100 | sis-co-50 | IVS3-1G>A | ||
MX | Rectal | 35 | >100 | 2 mesenteric desmoids; gastric polyps | mom died at 54 of a “tumor between heart & lungs” | 3709delCA | 15 |
GU | None | 39 | >100 | maun-co mass, not ca-49 | del exon 6-15 | ||
MX | Rectal | 26 | Polyposis, # unknown | abdominal desmoid; 2 pilomatrixomas | mom-ut-45, mgm-GI ca-75 | 3927del5 | 15 |
HO | Sigmoid descending colon | 42 | >100 | gastric polyps | mgm-ut-35 | E268X | 7 |
MX | Rectal | 33 | >100 | pun-“some polyps” | 3183del5 | 15 | |
HO | Tubular adenoma high-grade dysplasia+ | 42 | >100 | gastric polyps; duodenal polyps | maun-br-20 | pending | |
MX | None | 35 | >100 | gastric polyps; duodenal polyp | none | pending | |