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Table 1

From: Colorectal cancer risk in patients with inflammatory bowel disease and Lynch syndrome

Case #

 

1

2

3

4

5

Gender

 

M

F

F

M

F

Ethnicity

 

Caucasian

Jewish

Caucasian

Caucasian

Caucasian

MMR Mutation

 

MLH1

MSH2

MSH2

MSH2

MSH6

Age of IBD dx

 

27

20

27

32

23

Site of IBD

 

Ileum

Pancolitis

Pancolitis

Proctitis

Pancolitis

Colectomy, age

 

21

57

43

44

63

Cancer/dysplasia

 

CRC dx 21

LGC*

None

TVA/HGD** dx 44

Endometrial dx 57

Smoking hx

 

N

Y

N

Y

N

IBD medication

5-ASA

N

Y

Y

Y

Y

 

Steroids

N

Y

Y

N

Y

 

Antibiotics

N

Y

Y

Y

N

Age of CRC in 10 or 20 kin

# of kin

2

3

2

4

5

 

Mean age

40.5

30.7

35.5

49.7

78.4

  1. *LGD – low-grade dysplasia on random screening biopsy
  2. **TVA/HGD – tubulovillous adenoma with foci of high-grade dysplasia