Table 4 The age of hereditary cancer diagnostics and cancer-related death by population screening data.
From: Population screening for hereditary and familial cancer syndromes in Valka district of Latvia
Syndrome | Age of diagnosis | Age of death | ||
|---|---|---|---|---|
Interval (years) | Mean (95% CIM) | Interval (years) | Mean (95% CIM) | |
HBC/g1 | 40 - 55 | 47.5 (37.1 - 57.8) | 50 - 60 | 54.7 (50.0 - 59.4) |
HBC1/g2 | 20 - 70 | 38.0 (36.2 - 39.7) | 26 - 78 | 44.7 (41.7 - 47.7) |
HBC2/g2 | 25 - 82 | 51.8 (48.9 - 54.6) | 25 - 66 | 60.9 (56.7 - 65.1) |
HBOC/g1 | 34 - 82 | 61.0 (46.9 - 75.0) | 58 - 85 | 71.4 (54.9 - 87.9) |
HBOC1/g2 | 40 - 60 | 48.8 (44.2 - 53.3) | 47 - 69 | 54.3 (42.3 - 66.3) |
HBOC2/g2 | 18 - 86 | 56.6 (51.8 - 61.4) | 23 - 87 | 66.1 (61.2 - 71.0) |
HOC/g1 | 34 - 70 | 49.7 (4.0 - 95.4) | 72 | 72 |
HOC/g2 | 45 - 70 | 54.2 (46.4 - 61.9) | 47 - 72 | 57.2 (50.1 - 64.3) |
HNPCC/g1 | 30 - 77 | 54.2 (50.2 - 58.2) | 28 - 89 | 61.7 (54.2 - 69.2) |
CRC | 36 - 77 | 59.3 (53.8 - 64.8) | 28 - 89 | 61.5 (52.9 - 70.0) |
E | 30 - 65 | 48.4 (43.4 - 53.4) | 37 - 72 | NA |
HNPCC/g2 | 27 - 82 | 53.7 (49.1 - 58.3) | 28 - 88 | 55.5 (49.5 - 61.5) |
CRC | 28 - 82 | 55.2 (49.1 - 61.3) | 32 - 88 | 56.7 (49.9 - 63.5) |
E | 27 - 72 | 50.5 (43.0 - 58.0) | 28 - 73 | 51.2 (33.1 - 69.3) |
FCC/g2 | 41 - 89 | 72.0 (67.3 - 76.7) | 52 - 90 | 76.3 (73.1 - 79.5) |
HEC/g1 | 40 - 75 | 52.1 (47.2 - 57.0) | 44 - 76 | 57.7 (49.6 - 65.8) |
HEC/g2 | 30 - 81 | 48.5 (44.4 - 52.6) | 35 - 87 | 58.7 (53.6 - 63.8) |
FEC/g1 | 52 - 90 | 66.3 (63.0 - 69.6) | 54 - 91 | 71.7 (68.6 - 74.8) |
FEC1/g2 | 60 - 78 | 67.0 (53.1 - 80.9) | 65 - 86 | 79.2 (69.0 - 84.4) |
FEC2/g2 | 26 - 82 | 57.6 (49.9 - 65.3) | 26 - 83 | 63.3 (54.7 - 71.9) |
FLC/g1 | 35 - 78 | 56.0 (53.0 - 59.0) | 36 - 79 | 57.1 (54.1 - 60.1) |
FLC/g2 | 18 - 90 | 58.5 (56.1 - 60.9) | 13 - 90 | 61.2 (59.1 - 63.3) |
FLC/g3 | 18 - 90 | 57.9 (55.9 - 59.9) | 13 - 90 | 61.2 (58.5 - 62.1) |
HGC/g1 | 30 - 83 | 56.9 (53.4 - 66.3) | 30 - 90 | 58.3 (55.3 - 61.3) |
HGC/g2 | 34 - 95 | 62.5 (60.1 - 64.8) | 37 - 96 | 65.6 (63.4 - 67.6) |
HPC/g1 | 70 - 74 | 72.0 (67.0 - 76.9) | 72 | NA |
HPC/g2 | 35 - 75 | 56.8 (52.8 - 60.8) | 37 - 80 | 59.7 (54.6 - 64.8) |
HPC/g3 | 35 - 75 | 57.7 (53.3 - 62.1) | 37 - 80 | 60.7 (55.0 - 66.4) |
FBlaC/g1 | 60 - 75 | 67.5 (53.7 - 81.3) | 65 - 75 | 70.3 (65.6 - 75.0) |
FBlaC/g2 | 61 - 87 | 71.8 (67.3 - 76.3) | 72 - 92 | 79.3 (74.1 - 84.5) |
FBlaC/g3 | 60 - 87 | 70.7 (66.7 - 74.7) | 65 - 92 | 75.7 (71.6 - 79.8) |
FHemT/g1 | 45 - 61 | 50.7 (28.4 - 73.0) | 46 - 50 | 48.0 (22.6 - 73.4) |
FHemT/g2 | 3 - 88 | 47.1 (37.5 - 56.7) | 4 - 90 | 49.9 (39.7 - 60.1) |
FHemT/g3 | 3 - 88 | 47.5 (38.9 - 56.1) | 4 - 86 | 49.8 (40.5 - 59.1) |
FPanC/g1 | 51 - 72 | 61.6 (57.3 - 65.9) | 51 - 83 | 63.4 (58.2 - 68.6) |
FBT/g1 | 59 - 60 | 59.7 (58.3 - 61.1) | 50 - 65 | 59.7 (54.3 - 65.1) |
FBT/g2 | 2 - 77 | 41.8 (32.0 - 51.6) | 2 - 75 | 45.2 (35.9 - 54.5) |
FBT/g3 | 2 - 77 | 43.9 (35.0 - 52.8) | 2 - 77 | 47.8 (39.7 - 55.9) |