From: Cancer and Lhermitte-Duclos disease are common in Cowden syndrome patients
General | Physical examination beginning at age 18 or 5 years before the diagnosis of breast or thyroid cancer in the family. |
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Thyroid | Baseline ultrasound thyroid examination at age 18 and consider yearly thereafter. |
Skin | Annual dermatologic exam. |
Colon | None. |
Breast [female] | For those without a family history of breast cancer, self breast examination and clinical breast examination are recommended to commence at ages 18 and 25, respectively. Also, mammography and breast magnetic resonance imaging are recommended to begin at ages 30 to 35. Consider prophylactic mastectomy. |
Endometrial [female] | Educate on symptoms and consider enrollment in a clinical trial. |