From: Cancer and Lhermitte-Duclos disease are common in Cowden syndrome patients
Site | 20 yrs | 30 yrs | 40 yrs | 50 yrs | 60 yrs | 70 yrs |
---|---|---|---|---|---|---|
All cancers | 9% (6-13) | 18% (13-24) | 35% (29-43) | 63% (46-70) | 78% (70-85) | 89% (80-95) |
Breast [female] | 0 | 4% (2-10) | 19% (12-27) | 53% (42-63) | 73% (61-83) | 81% (66-90) |
Lhermitte-Duclos | 4% (2-8) | 10% (6-15) | 13% (9-19) | 21% (15-28) | 21% (15-28) | 32% (19-49) |
Thyroid | 4% (0-5) | 5% (10-29) | 9% (6-15) | 17% (12-25) | 21% (14-29) | 21% (14-29) |
Endometrium | 1% (0-5) | 1% (0-5) | 1% (0-5) | 9% (5-19) | 19% (10-32) | 19% (10-32) |
Colon and rectum | 0 | 0 | 0 | 3% (1-10) | 13% (7-25) | 16% (8-24) |
Kidney | 0 | 1% (0-4) | 1% (0-4) | 3% (1-8) | 7% (3-16) | 15% (6-32) |