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Figure 1 | Hereditary Cancer in Clinical Practice

Figure 1

From: Cancer and Lhermitte-Duclos disease are common in Cowden syndrome patients

Figure 1

A clinical array of the cancer and Lhermitte-Duclos disease (LDD) diagnoses in the 136 female Cowden syndrome patients included in the study. Each column of rectangles represents an individual patient. A diagnosis is indicated by a shaded box containing a "1". Rows represent cancer or LDD diagnosis: BCA (pink) - breast cancer (n = 61 cases); BBC (magenta) - bilateral breast cancer (n = 21 cases); LDD (teal) - Lhermitte-Duclos disease (n = 24 cases); TCA (yellow) - thyroid cancer (n = 23 cases); ECA (violet) - endometrial cancer (n = 12 cases); RCA (blue) - renal cancer (n = 5 cases); SCA (green) - skin cancer (n = 8 cases); Oth (grey) - other cancers (n = 12 cases); CRC (brown) - colorectal cancer (n = 5 cases). Patients were sorted into groups and subgroups by cancer diagnosis (hierarchical sorting). This aids identification of the clustering of one cancer diagnosis with another. Patients were first sorted into those with and without breast cancer. Those with breast cancer were then sorted into those with and without bilateral breast cancer. Each of the subgroups (breast cancer, bilateral breast cancer, and no breast cancer) were then sorted into those with and without LDD and then into those with and without thyroid cancer. Figure formatting taken from Faghri and others [14].

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