Table 1 Characteristics of the 167 BRCA1 mutation carriers
From: Survival in Norwegian BRCA1 mutation carriers with breast cancer
no(%) | ||
|---|---|---|
Age | <30 | 6(3.6) |
30–39 | 47(28.1) | |
40–49 | 70(41.9) | |
50–59 | 33(19.8) | |
60–69 | 7(4.2) | |
>/= 70 | 4(2.4) | |
Type of operation | Mastectomy | 125(74.9) |
BCT | 40(24.0) | |
Ablatio simplex | 1(0.6) | |
Halsteds | 1(0.6) | |
Stage | 1(T1-2N0) | 104(62.3) |
2(T1-2N1) | 54(32.3) | |
3(T1-2N2-3, T3-4N0-3) | 9(5.4) | |
Size | T1(tumour ≤2 cm) | 83(49.7) |
T2(tumour >2 cm, ≤5 cm | 71(42.5) | |
T3(tumour >5 cm) | 6(3.6) | |
T4(Infiltration in skin or muscle, inflammatory) | 3(1.8) | |
Unknown | 4(2.4) | |
Grade | I | 2(1.2) |
II | 21(12.6) | |
III | 82(49.1) | |
Unknown, incl. DCIS, LCIS | 62(37.1) | |
Nodal status | Negative | 101(60.5) |
Positive | 66(39.5) | |
ER status | Negative | 86(51.5) |
Positive | 45(26.9) | |
Unknown | 36(21.6) | |
Type | Ductal | 137(82.0) |
Medullary | 11(6.6) | |
Lobular | 5(3.0) | |
DCIS | 6(3.6) | |
LCIS | 3(1.8) | |
Anaplastic | 1(0.6) | |
Tubular | 1(0.6) | |
Mucinous | 1(0.6) | |
Mixed ductal/lobular | 1(0.6) | |
Mixed medullary/ductal | 1(0.6) | |
Chemotherapy | Yes | 93(55.7) |
No | 74(44.3) | |
Contralateral cancer | Yes | 42(25.1) |
No | 110(65.9) | |
Prophylactic mastectomy contralat | 13(7.8) | |
Reduction contralat | 2(1.2) |