Table 3 Characteristics of MUTYH Y165C and G382D heterozygous mutation carriers
From: Genetic variants in MUTYH are not associated with endometrial cancer risk
Characteristics | Y165C – patient 1 | G382D – patient 2 | G382D – patient 3 |
|---|---|---|---|
Year of Birth | 1933 | 1935 | 1951 |
BMI (kg/m2) | >30 | 25–30 | 25–30 |
Age of Diagnosis of Endometrial cancer (years) | 71 | 70 | 52 |
Age of Menarche | 15 | 16 | 15 |
Age of Menopause | 55 | 45 | 52 |
No. of Children | 0 | 3 | 2 |
Oral Contraceptive | Never Use | Never | Never |
Other Diseases | High Blood Pressure Ovarian Cancer Colorectal Cancer | High Blood Pressure Diabetes | Diabetes |
Family History of Sister Cancer | Colorectal cancer Mother & Maternal Aunt Breast Cancer | Father Colorectal Brother Leukaemia | None |
Stage of Cancer | Unknown | 1B | Mixed Mullerian Malignant Tumour |
Grade of Cancer | 1 | 1 | 3 |
Histology | Adenocarcinoma | Adenocarcinoma | Mixed Mullerian Malignant Tumour |
Recurrence | None | None | None |
Smoker | Never | Current | Never |
Alcohol | Non-Drinker | Non-Drinker | Non-Drinker |