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Table 1 Study population characteristics

From: Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management

  MLH1 MSH2 MSH6 Total
Families 26 20 21 67
Mutation carriers 70 67 109 246
Males (%) 28(40) 28 (42) 36 (33) 92 (37)
Subjects with colorectal cancer (%) 36 (51) 21 (31) 26 (24) 83 (34)
Subjects with endometrial carcinoma 7 (10) 9 (13) 21 (19) 37 (15)
Subjects with other Lynch associated cancer (%)*     
Ovarian carcinoma 1 (1) 3 (4) 6 (6) 10 (4)
Small bowel cancer 1 (1) 2 (3) 0 (0) 3 (1)
Transitional cell carcinoma 0 (0) 3 (4) 3 (3) 6 (2)
  1. * No histological proven stomach cancers were reported.