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Table 1 Study population characteristics

From: Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management

 

MLH1

MSH2

MSH6

Total

Families

26

20

21

67

Mutation carriers

70

67

109

246

Males (%)

28(40)

28 (42)

36 (33)

92 (37)

Subjects with colorectal cancer (%)

36 (51)

21 (31)

26 (24)

83 (34)

Subjects with endometrial carcinoma

7 (10)

9 (13)

21 (19)

37 (15)

Subjects with other Lynch associated cancer (%)*

    

Ovarian carcinoma

1 (1)

3 (4)

6 (6)

10 (4)

Small bowel cancer

1 (1)

2 (3)

0 (0)

3 (1)

Transitional cell carcinoma

0 (0)

3 (4)

3 (3)

6 (2)

  1. * No histological proven stomach cancers were reported.