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Figure 1 | Hereditary Cancer in Clinical Practice

Figure 1

From: Penetrance of HNPCC-related cancers in a retrolective cohort of 12 large Newfoundland families carrying a MSH2 founder mutation: an evaluation using modified segregation models

Figure 1

Segregation model estimates of penetrance for any HNPCC, CRC and EC. Age-specific cumulative risks and 95% confidence intervals of hereditary nonpolyposis colorectal cancer related cancers [(a) any hereditary nonpolyposis colorectal cancer, (b) colorectal cancer, (c) endometrial cancer] among mutation carriers and non-carriers specified by gender, based on the segregation analyses.

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Hereditary Cancer in Clinical Practice

ISSN: 1897-4287