Table 3 Clinico-pathological characteristics of breast and Ovarian cancer cases
From: Molecular genetics analysis of hereditary breast and ovarian cancer patients in India
Clinico-pathological features | 65 Unilateral breast cases in number (%) | 6 Bilateral breast cases in number (%) | 14 Ovarian cases in number (%) |
|---|---|---|---|
Age (years) | Â | Â | Â |
35 | 37 (56.8%) | 5 (83.3%) | 6 (42.8%) |
36–45 | 17 (26.1%) | 1 (16.6%) | 3 (21.4%) |
46–55 | 9 (13.8%) | - | 3 (21.4%) |
56–65 | 1 (1.5%) | - | - |
>65 | 1 (1.5%) | - | 2 (14.2%) |
Stage | Â | Â | Â |
I | 8 (12.5%) | Lt: 2(33.2%) Rt:1(16.6%) | 2 (14.2%) |
II | 15 (23.0%) | Lt: 2(33.2%) Rt: - | - |
III | 37 (56.8%) | Lt: – Rt:4(66.6%) | 7 (50%) |
IV | 2 (3.1%) | Lt: 2(33.2%) Rt:1(16.6%) | 3 (21.4%) |
NK | 3 (4.6%) | - | 2 (14.4%) |
Grade | Â | Â | Â |
I | 30 (46.2%) | Lt:4(66.6%) Rt:1(16.6%) | 3 (21.4%) |
II | 18 (27.3%) | Lt:1(16.6%) Rt:3(50%) | 2 (14.2%) |
III | 10 (15.4%) | Lt: – Rt: - | 3 (21.4%) |
NK | 7 (10.1%) | Lt:1 (16.6%)Rt:2(33.2%) | 6 (42.8%) |
Disease Status | Â | Â | Â |
Disease free | 43 (66.3%) | 3 (50%) | 5 (35.7%) |
Recurrence & disease present | 9 (14.0%) | 1 (16.6%) | 6 (42.8%) |
Recurrence & disease free | 1 (1.5%) | - | - |
Default | 6 (9.1%) | 1 (16.6%) | 1 (7.1%) |
Not treated at CI | 6 (9.1%) | 1 (16.6%) | 2 (14.2%) |
Type | Â | Â | Â |
IDC | 53 (82.1%) | Lt:5(83.3%)Rt:5(83.3%) | - |
Medullary | 4 (6.2%) | - | Â |
Mucinous | 1 (1.6%) | - | Â |
Others | 3 (4.6%) | Lt:1(16.6%)Rt:1(16.6%) | Â |
NK | 4 (5.5%) | - | Â |
ER | Â | Â | Â |
Positive | 15/55 (27.3%) | 0 | - |
Negative | 40/55 (72.7%) | 4/4 (100%) | Â |
PR | Â | Â | Â |
Positive | 17/53 (32.0%) | 0 | - |
Negative | 36/53 (68.0%) | 4/4 (100%) | Â |
c-erbB2 | Â | Â | Â |
Positive | 15/46 (32.6%) | 1/4(25%) | - |
Negative | 31/46 (67.4%) | 3/4 (75%) | Â |
P53 | Â | Â | Â |
Positive | 21/44 (47.7%) | 1/4(25%) | - |
Negative | 23/44 (52.3%) | 3/4 (75%) | Â |