Table 3 Frequency of identified panel of markers in all breast cancers diagnosed at age above 50 and controls [9]
Gene/Marker | Cancer | Controls |
|---|---|---|
BRCA1 | 2.1% (14/667) | 0% (0/667) |
CHEK2 | 11% (72/653) | 4.8% (32/667) |
p53 | 11% (64/581) | 5.4% (34/635) |
TNR | 55.9% (289/517) | 45.3% (272/601) |
FGFR - nAA | 68.9% (157/228) | 60.8% (200/329) |
BRCA2 | 5.6% (4/71) | 2.3% (3/129) |
XPD - CC/AA | 13.4% (9/67) | 6.3% (8/126) |
NOD2 | 13.8% (8/58) | 6.8% (8/118) |
XPD - GG | 48% (24/50) | 35.5% (39/110) |
Any marker | 96.1% (641/667) | 89.4% (596/667) |
Statistic | P = 2.4 × 10 -6 | |