Table 1 Frequency of identified panel of markers in unselected breast Cancers and controls [9]
Gene/Marker | Cancer | Controls |
|---|---|---|
BRCA1 | 2.7% (26/977) | 0% (0/977) |
CHEK2 | 11.9% (113/951) | 6% (59/977) |
p53 | 10.1% (85/838) | 5.7% (52/918) |
TNR | 55.6% (419/753) | 45.8% (397/866) |
FGFR - GG | 18.3% (61/334) | 13.9% (65/469) |
CDKN2A | 7% (19/273) | 5.4% (22/404) |
XPD - GG | 41% (104/254) | 36.4% (139/382) |
XPD - CC/AA | 17.3% (26/150) | 14% (34/243) |
BRCA2 | 7.3% (9/124) | 4.8% (10/209) |
XPD - AA | 20% (23/115) | 18.6% (37/199) |
Any marker | 90.6% (885/977) | 83.4% (815/977) |
Statistic | P = 3 × 10 -6 | |