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Table 2 Comparison of the frequency of BRCA1 mutations in 1793 patients with prostate cancer and 4570 controls

From: Selected aspects of inherited susceptibility to prostate cancer and tumours of different site of origin

Mutation Number of carriers (frequency) OR 95% CI p
  cases (n = 1793) controls (n = 4570)    
  No. (%) No. (%)    
BRCA1 8 (0.45) 22 (0.48) 0.9 0.4–2.1 1.0
C61G 3 (0.17) 3 (0.07) 2.6 0.5–12.7 0.5
4153delA 4 (0.22) 2 (0.04) 5.1 0.9–27.9 0.1
5382insC 1 (0.06) 17 (0.37) 0.15 0.02–1.1 0.06
C61G or 4153delA* 7 (0.39) 5 (0.11) 3.6 1.1–11.3 0.045
  1. CI – confidence interval; OR – odds ratio; p – p-value
  2. *when 5382insC is excluded, as unlikely pathogenic for prostate cancer in the Polish population