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Table 8 Lys751Gln/Gly156Gly genotypes among melanoma and control groups

From: Some Molecular and Clinical Aspects of Genetic Predisposition to Malignant Melanoma and Tumours of Various Site of Origin

Lys751Gln Gly156Gly Melanoma (MM) Newborns 95% CI p OR
   (n = 424) (n = 1052)    
AA AA 56 (13.2%) 157 (14.9%) - n.s. 0.9
AA CA 70 (16.5%) 182 (17.3%) - n.s. 1
AA CC 19 (4.5%) 62 (5.9%) - n.s. 0.7
AC AA 7 (1.65%) 25 (2.4%) - n.s. 0.7
AC CA 130 (30.66%) 318 (30.2%) - n.s. 1
AC CC 66 (15.57%) 153 (14.6%) - n.s. 1.1
CC AA 2 (0.50%) 2 (0.2%) - n.s. 2.5
CC CA 9 (2.12%) 36 (3.4%) - n.s. 0.6
CC CC 65 (15.3%) 117 (11.12%) 1.044–2.006 0.03 (0.18) 1.4
CC CC MM = 501 117 (11.12%) - n.s. 1.1
   (n = 172)     
   21 (12.2%)     
CC CC MM>501 117 (11.12%) 1.170–2.491 0.007 (0.042) 1.7
   (n = 250)     
   44 (17.6%)     
  1. p value calculated with the ÷2 test (Bonferroni adjusted value in parantheses)
  2. 1age at onset unknown in two cases of melanoma