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Table 3 Genes commonly up-regulated 2-fold or more in colorectal FAP polyps compared to normal colon

From: Gene Expression Profiling in Familial Adenomatous Polyposis Adenomas and Desmoid Disease

Symbol Gene Name
Cell Cycle Control  
CCNB2 Cyclin B2
CDKN3 Cyclin-dependent kinase inhibitor 3
AURKB Aurora kinase B
Cell Cycle  
HCAP-G Chromosome condensation protein G
PRC1 Protein regulator of cytokinesis 1, tv-1
KIF2C Kinesin family member 2C
CHC1 Chromosome condensation 1
SMC4L1 SMC4 structural maintenance of chromosome 4-like 1 (yeast)
Pfs2 DNA replication complex GINS protein PSF2
RNASEH2A Ribonuclease H2, large subunit
Transcription/Transcriptional Regulation
FLJ20315 Hypothetical protein FLJ20315
TBPL1 TBP-like 1
LOC89958 Hypothetical protein LOC89958
HMGN1 High-mobility group nucleosome binding domain 1
ZNF22 Zinc finger protein 22 (KOX 15)
PTTG1 Pituitary tumour-transforming 1
NFE2L3 Nuclear factor (erythroid-derived 2)-like 3
SOX9 SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)
SLC12A2 Solute carrier family 12 (sodium/potassium/chloride transporters) member 2
CLCA1 Chloride channel, calcium activated, family member 1
LCN2 Lipocalin 2 (oncogene 24p3)
SORD Sorbitol dehydrogenase
TPRT Trans-prenyltransferase
QTRT1 Queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase)
PAICS Phosphoribosylaminoimidazole carboxylase, Phosphoribosylaminoimidazole succinocarboxamide synthetase
DPH2L2 DPH2-like 2 (S. cerevisiae), tv-1
ALOX5 Arachidonate 5-lipoxygenase
IARS Isoleucine-tRNA synthetase, tv-short
TK1 Thymidine kinase 1, soluble
EPHB2 EphB2 (EPHB2), tv-1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) tv-1
MAP17 Membrane-associated protein 17
GDF15 Growth differentiation factor 15
RACGAP1 Rac GTPase activating protein 1
mRNA Processing  
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
THOC3 THO complex 3
Cell Adhesion  
C20orf42 Chromosome 20 open reading frame 42
UK114 Translational inhibitor protein p14.5
ZCWCC2 Zinc finger, CW-type with coiled-coil domain 2
KIAA1324 Maba1
FLJ10514 Hypothetical protein FLJ10514
ENC1 Ectodermal-neural cortex (with BTB-like domain)
PTTG2 Pituitary tumour-transforming 2
C21orf59 Chromosome 21 open reading frame 59
WDR12 WD repeat domain 12
LXN Latexin protein
KIAA1892 KIAA1892
KIAA1797 KIAA1797
GLCE Glucuronyl C5-epimerase
KIAA0101 KIAA0101 gene product
RRP46 Exosome component Rrp46
S100P S100 calcium binding protein P
PRDX4 Peroxiredoxin 4
FLJ20366 Hypothetical protein FLJ20366
F12 Coagulation factor XII (Hageman factor)
IGFBP2 Insulin-like growth factor binding protein 2 (36 kD)
GW112 Differentially expressed in hematopoietic lineages
C10orf3 Chromosome 10 open reading frame 3
ATOH8 Atonal homolog 8 (Drosophila)
MFN1 Mitofusin 1, nuclear gene encoding mitochondrial protein, tv-2
QPCT Glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
UBE2S Ubiquitin-conjugating enzyme E2S