Table 2 Genes commonly down-regulated more than 2-fold in all FAP polyps compared to normal colon
From: Gene Expression Profiling in Familial Adenomatous Polyposis Adenomas and Desmoid Disease
Symbol | Gene Name |
|---|---|
Cell Cycle Control | Â |
PPP3CB | Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) |
Transport | Â |
SLC20A1 | Solute carrier family 20 (phosphate transporter), member 1 |
P2RX4 | Purinergic receptor P2X, ligand-gated ion channel, 4, tv-2 |
Metabolism | Â |
PC | Pyruvate carboxylase, nuclear gene encoding mitochondrial protein, tv-2 |
PRSS3 | Protease, serine, 3 (mesotrypsin) |
ST6GALNAC6 | CMP-NeuAC: (beta)-N-acetylgalactosaminide (alpha) 2,6-sialyltransferase member IV |
Signal Transduction | Â |
IL2RG | Interleukin 2 receptor, gamma (severe combined immunodeficiency) |
TJP3 | Tight junction protein 3 (zona occludens 3) |
Cell Adhesion | Â |
CDC42 | Cell division cycle 42 (GTP binding protein, 25 kDa), tv-2 |
GSN | Gelsolin (amyloidosis, Finnish type), tv-2 |
TAGLN | Transgelin |
Apoptosis | Â |
DAPK3 | Death-associated protein kinase 3 |
Structural | Â |
KRT19 | Keratin 19 |
TPM2 | Tropomyosin 2 (beta) |
Other | Â |
CTGF | Connective tissue growth factor |
EPS8L2 | EPS8-like 2 |
LRRC1 | Leucine rich repeat containing 1 |
NS5ATP13TP2 | NS5ATP13TP2 protein |
PTPRR | Protein tyrosine phosphatase, receptor type, R, tv-2 |
RICH1 | RhoGAP interacting with CIP4 homologs 1 |
SMTN | Smoothelin, tv-2 |