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Table 2 Genes commonly down-regulated more than 2-fold in all FAP polyps compared to normal colon

From: Gene Expression Profiling in Familial Adenomatous Polyposis Adenomas and Desmoid Disease

Symbol Gene Name
Cell Cycle Control  
PPP3CB Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta)
Transport  
SLC20A1 Solute carrier family 20 (phosphate transporter), member 1
P2RX4 Purinergic receptor P2X, ligand-gated ion channel, 4, tv-2
Metabolism  
PC Pyruvate carboxylase, nuclear gene encoding mitochondrial protein, tv-2
PRSS3 Protease, serine, 3 (mesotrypsin)
ST6GALNAC6 CMP-NeuAC: (beta)-N-acetylgalactosaminide (alpha) 2,6-sialyltransferase member IV
Signal Transduction  
IL2RG Interleukin 2 receptor, gamma (severe combined immunodeficiency)
TJP3 Tight junction protein 3 (zona occludens 3)
Cell Adhesion  
CDC42 Cell division cycle 42 (GTP binding protein, 25 kDa), tv-2
GSN Gelsolin (amyloidosis, Finnish type), tv-2
TAGLN Transgelin
Apoptosis  
DAPK3 Death-associated protein kinase 3
Structural  
KRT19 Keratin 19
TPM2 Tropomyosin 2 (beta)
Other  
CTGF Connective tissue growth factor
EPS8L2 EPS8-like 2
LRRC1 Leucine rich repeat containing 1
NS5ATP13TP2 NS5ATP13TP2 protein
PTPRR Protein tyrosine phosphatase, receptor type, R, tv-2
RICH1 RhoGAP interacting with CIP4 homologs 1
SMTN Smoothelin, tv-2