Pedigree of family 1 with multiple myeloma. Diagnosis and age of diagnosis are given, as well as age of death. Solid blocks represent patients with multiple myeloma; open blocks represent patients without multiple myeloma. Diagonal lines indicate deceased individuals, and the arrow indicates the proband. The roman numbers in the left margin refer to the different generations. MM = multiple myeloma; Lu = lung cancer; L = leukaemia; D = deceased; number in parenthesis = age of onset, current age, or age of death.