Selected aspects of genetic counselling for BRCA1 mutation carriers

Table 12 Number by age of mutation positive and negative first-degree female relatives of BRCA1 mutation carriers (both studies together)

Year of birth	Number of carriers	Number of non-carriers	Transmission ratio (%)	p
< 1950	10	11	48	0.800
1951-1960	40	29	58	0.300
1961-1970	36	28	56	0.300
1971-1980	71	40	64	0.003
> 1981	42	49	46	0.900
Total	199	157	56	0.030

ISSN: 1897-4287