Table 1 Genotype and allele distribution of variants in the ARLTS1 gene in BCC cases and controls
From: ARLTS1 polymorphisms and basal cell carcinoma of the skin
Genotype/Allele | Cases* | Controls | OR (95%CI) | P-value |
|---|---|---|---|---|
S99S (297G>A) | Â | Â | Â | Â |
   GG | 487 (92.2) | 490 (91.9) | 1.0 (referent) |  |
   GA | 41 (7.7) | 43 (8.1) | 1.1 (0.7-1.7) | 0.81** |
   G-allele | 1015 (96.1) | 1023 (96.0) | 1.0 (referent) |  |
   A-allele | 41 (3.9) | 43 (4.0) | 1.1 (0.7-1.6) | 0.81 |
P131L (392C>T) | Â | Â | Â | Â |
   CC | 496 (93.9) | 508 (95.3) | 1.0 (referent) |  |
   CT | 32 (6.1) | 25 (4.7) | 1.3 (0.8-2.3) | 0.30 |
   C-allele | 1024 (97.0) | 1041 (97.7) | 1.0 (referent) |  |
   T-allele | 32 (3.0) | 25 (2.3) | 1.3 (0.8-2.3) | 0.31 |
L132L (396G>C) | Â | Â | Â | Â |
   GG | 527 (99.8) | 531 (99.6) | 1.0 (referent) |  |
   GC | 1 (0.2) | 2 (0.4) | 0.4 (0.1-4.0) | 0.40 |
   G-allele | 1055 (99.9) | 1064 (99.8) | 1.0 (referent) |  |
   C-allele | 1 (0.1) | 2 (0.2) | 0.4 (0.1-4.0) | 0.40 |
C148R (442T>C) | Â | Â | Â | Â |
   TT | 165 (31.3) | 155 (29.1) | 1.0 (referent) |  |
   TC | 250 (47.4) | 258 (48.4) | 0.9 (0.7-1.2) |  |
   CC | 113 (21.0) | 120 (22.5) | 0.9 (0.6-1.2) | 0.64 |
   T-allele | 580 (54.9) | 568 (53.3) | 1.0 (referent) |  |
   C-allele | 476 (45.1) | 498 (46.7) | 0.9 (0.8-1.1) | 0.36 |
W149X (446G>A) | Â | Â | Â | Â |
   GG | 519 (98.3) | 524 (98.3) | 1.0 (referent) |  |
   GA | 9 (1.7) | 9 (1.7) | 1.5 (0.6-4.0) | 0.41 |
   G-allele | 1047 (99.2) | 1057 (99.2) | 1.0 (referent) |  |
   A-allele | 9 (0.8) | 9 (0.8) | 1.5 (0.5-3.5) | 0.41 |